I’ve hit two bugs early on in my first two playthroughs.
The first one was a bug that happened immediately at the start of the game, when I got my first aspirations. Only one of them actually got assigned properly, the other two were blank. Even the single “Become friends with Astra” mission that was visible didn’t complete when I accepted her friend request.
The second bug hit on a second attempt at the game. After a few days, I got a popup at the start of the day saying “you have a new spacebook message”, then immediately I got the “yellow alert” dialog, which couldn’t be closed. Here is a zipped up version of the “output_log.txt” file. It seems to be reproducible when I load the save from the previous evening, so if you’d like, I can upload that too (though you’ll have to tell me what files are needed).