[win] Game crashes at startup

I was never able to start the game : I get only a black screen and a Runtime error :
Microsoft Visual C++ Runtime library
Runtime error !
Program :
This application has requested the runtime to terminate in an unusual way.
Please contact technical support.

Could you help me to solve this issue ?

Please find below the log :

Initialize engine version: 4.7.1f1 (68064779abd0)
GfxDevice: creating device client; threaded=1
Direct3D:
Version: Direct3D 9.0c [aticfx32.dll 8.17.10.1452]
Renderer: AMD Radeon R7 200 Series
Vendor: ATI
VRAM: 2023 MB (via DXGI)
Caps: Shader=30 DepthRT=1 NativeDepth=1 NativeShadow=1 DF16=1 INTZ=1 RAWZ=0 NULL=1 RESZ=1 SlowINTZ=1
Begin MonoManager ReloadAssembly
Platform assembly: F:\Jeux\Steam\steamapps\common\Big Pharma\Big Pharma_Data\Managed\UnityEngine.dll (this message is harmless)
Loading F:\Jeux\Steam\steamapps\common\Big Pharma\Big Pharma_Data\Managed\UnityEngine.dll into Unity Child Domain
Platform assembly: F:\Jeux\Steam\steamapps\common\Big Pharma\Big Pharma_Data\Managed\Assembly-CSharp-firstpass.dll (this message is harmless)
Loading F:\Jeux\Steam\steamapps\common\Big Pharma\Big Pharma_Data\Managed\Assembly-CSharp-firstpass.dll into Unity Child Domain
Platform assembly: F:\Jeux\Steam\steamapps\common\Big Pharma\Big Pharma_Data\Managed\Assembly-CSharp.dll (this message is harmless)
Loading F:\Jeux\Steam\steamapps\common\Big Pharma\Big Pharma_Data\Managed\Assembly-CSharp.dll into Unity Child Domain
Platform assembly: F:\Jeux\Steam\steamapps\common\Big Pharma\Big Pharma_Data\Managed\UnityEngine.UI.dll (this message is harmless)
Loading F:\Jeux\Steam\steamapps\common\Big Pharma\Big Pharma_Data\Managed\UnityEngine.UI.dll into Unity Child Domain

  • Completed reload, in 0.692 seconds
    Initializing input. Input initialized.desktop: 1920x1080 60Hz; virtual: 1920x1080 at 0,0
    Mismatched serialization in the builtin class ‘AudioClip’. (Read 24 bytes but expected 3913628 bytes)

(Filename: Line: 1174)

Mismatched serialization in the builtin class ‘AudioClip’. (Read 24 bytes but expected 3957776 bytes)

(Filename: Line: 1174)

Mismatched serialization in the builtin class ‘AudioClip’. (Read 24 bytes but expected 4521928 bytes)

(Filename: Line: 1174)

Mismatched serialization in the builtin class ‘AudioClip’. (Read 24 bytes but expected 4069976 bytes)

(Filename: Line: 1174)

Platform assembly: F:\Jeux\Steam\steamapps\common\Big Pharma\Big Pharma_Data\Managed\System.Core.dll (this message is harmless)
Platform assembly: F:\Jeux\Steam\steamapps\common\Big Pharma\Big Pharma_Data\Managed\System.dll (this message is harmless)

Hi there, I’m sorry to hear you’re having problems running the game. With a full on crash like this, there should be an additional error log called error.log in the installation directory, next to Big Pharma.exe.

Can you see if you can find it an post it below?

In the mean time, could you also try the following:

  1. Running the game in administrator mode
  2. Updating your graphic card drivers.
  3. Disabling your Antivirus software (if any)
  4. Disabling any GPU overclocking software (if any, the one that I know causes problems is EVGA precision).

I’m sorry for any inconvenience caused. Let me know how you get on.

Tim