Recently I bought Big Pharma and ran into issues running it on Linux Mint. Using the default Open Source Drivers for my system causes the game to not render graphics properly and makes navigating the menus difficult as clicking on the buttons does not always work. I was able to play through the first tutorial, but the graphics were not working.
To fix the graphical problem I upgraded to the proprietary drivers on my system, which first lead to the game not loading past the developer logos with the Steam Overlay enabled. Disabling the Steam Overlay allowed the game to load but it then would crash if you entered the ingredients tab(likely other tabs as well but I did not test further). Graphically the game worked and the menu buttons were no longer an issue, but crashing makes the game unplayable.
I have tested this on both the Steam Version, and the DRM Free Standalone. I believe the second issue is related to Unity3D not working properly with the proprietary drivers(unable to play Table Top Simulator either and saw it had logs in the Unity3D folder just like Big Pharma).
Comparison Album: http://imgur.com/a/UFn5U
Note: I had to boot up a live usb to take the open source Ati screenshots as I was unable to switch to them on my laptop.
Other System Details:
00:01.0 VGA compatible controller : Advanced Micro Devices, Inc. [AMD/ATI] Trinity [Radeon HD 7640G] [1002:9903] (prog-if 00 [VGA controller]) Subsystem: Acer Incorporated [ALI] Device [1025:0696] Flags: bus master, fast devsel, latency 0, IRQ 49 Memory at e0000000 (32-bit, prefetchable) [size=256M] I/O ports at 4000 [size=256] Memory at f0400000 (32-bit, non-prefetchable) [size=256K] Expansion ROM at <unassigned> [disabled] Capabilities: <access denied> Kernel driver in use: fglrx_pci OpenGL vendor string: Advanced Micro Devices, Inc. OpenGL renderer string: AMD Radeon HD 7640G OpenGL core profile version string: 4.3.13374 Core Profile Context 15.20.1013 OpenGL core profile shading language version string: 4.40 OpenGL core profile context flags: (none) OpenGL core profile profile mask: core profile OpenGL core profile extensions: OpenGL version string: 4.4.13374 Compatibility Profile Context 15.20.1013 OpenGL shading language version string: 4.40 OpenGL context flags: (none) OpenGL profile mask: compatibility profile OpenGL extensions: Machine: System: Acer product: Aspire V3-551 version: V2.13 Mobo: Acer model: VA50_CM Bios: Insyde version: V2.13 date: 05/09/2013