I only played the first four tutorials during lunch, but I’m already enjoying the concept of the game. e.g. by the second tutorial I was already itching to make that nausea go away – I suspect you can do it by decreasing the concentration a few times after you’ve upgraded, right? So I don’t have much feedback about the gameplay itself, but I have a few bugbears about the interface and accessibility!
These were entirely my own thoughts, and yet I come here to post them and find some match exactly to the poster above! Hopefully this mountain of negative appearing feedback won’t dissuade you from feeling good about the excellent game you’ve made – the feedback is here to try and improve it and make it even better 
In general the game is a very exciting concept, with a really nice nice look and feel about it. I like the music, though I don’t know if I will in 45 hours of playing 
ps: I like the auto-generated drug names (“tutorialis name bane” etc) 
Level select screen
Running in a 1280x720 window I had to scroll left to get to “tutorial”. So if I hadn’t moved my mouse towards beginner, I wouldn’t have known it existed. I was thinking of going for “Quick Start” but then thought there might be an order, so went left. Good job I did 
There’s also no visual indication that this selection thingy is a scrolling menu. Little left/right arrows would be appreciated.
Tutorial Text
The tutorial about research (mission 3?) fails to mention “process time”, which is clearly the important number that makes the pill printer so slow 
But apart from that the game mechanics are well explained by experimenting with the UI itself, and the tutorial text does a great job of explaining it anyway.
GUI stuff
Tutorial pop-ups: I assume they can re-size for different resolutions? Assuming they can, could they be made user resizeable, like a proper “window”? I like to read text in a different way than the box wants.
Concentration bar should run down the effects list lining them all up?
Is there a way to see what ingredient something will upgrade to before doing it, so you can plan thing out before just buying a bunch of machines to produce it?
I’m not colour blind, but have you done any UI tests with colour blind filters? Relying on identical brightness red/green to distinguish good/bad looks like it might be a problem. I haven’t played enough of the game to know if there’s another way for players to know if an effect is good or bad, but from what I saw of the let’s play videos, these effects can move/rotate around, so the player clearly needs to be keeping track of which is which and the only way to do so is via colour?
EDIT:
color-blindness.com/coblis-c … simulator/
I cropped one of my images below to just be the effects box, uploaded it, and yep, they look identical to most colour blind users.
Text
When I select the ingredient import station in the first tutorial, the text is really small. Switching to a 1280x960 window – it’s still really small. Infact it doesn’t appear to have changed, unlike the rest of the UI? Amusingly, the little images inside the tutorial box are BIGGER and more readable than the one in the top right that they’re meant to show! 
Here’s an image to illustrate. (Click to embiggen)

Compare the tutorial text + image there to the top right box.
In general a lot of the text is too small and blurry to be read properly.
Look at the highlighted pink bits in these images:


The HIRE/FIRE are literally 1 pixel wide, on a 1280x960 window!
The description for Basic Exploration is similiar, but it’s really blurry.
If you’re going to have text that small, experiment with not doing a linear filter/anti-aliasing on it.
Controls
So a right click drag moves. But a static right click deselects. Ok. But I kept deselecting whilst idly panning. Turns out I can right click to drag, and visiblly move about 3 pixels and still deselect
Perhaps middle button solely devoted to drag?
It seems quite easy to delete things with stationary RMB when trying to deselect stuff. Perhaps have a seperate ‘delete’ mode?
Personally I’m using the mouse to move. But it seems really, really weird for WASD/arrows to stop functioning when I select something to build. People will be baffled by this. Use QE to rotate, perhaps?
Can’t double click to move belts?
No band box selection/moving?
Keyboard shortcuts plz! ‘b’ or ‘1’ for belt or something 
Sound
Sound normalisation is a bit off. Or at least ‘music’ and ‘sound’ set to the same level don’t match in terms of loudness. The music is a lot quieter than the machinery sounds.