Linux user here, I purchased the Alpha tonight and spent half hour playing, using the Wine software to run Production Line on Ubuntu Linux.
It went really well actually, no crashes, smooth and decent looking.
Will give you more updates as I play more on Wednesday. Traveling to London tomorrow on business (booo hiss!).
Any other Linux users (i doubt it!) please post your bugs here so we can try and collate any issues which may be as a result of running on Linux / Wine.